Views:5 Author:Site Editor Publish Time: 2021-05-21 Origin:Site
Chlorophenols have been widely used as preservatives, disinfectants, pesticides and herbicides. These toxic chemicals are quite recalcitrant to degradation and can accumulate in the environment.
The structural formula is ClC6H4OH. There are 3 kinds of ortho, meta and para isomers. The counterpart is colorless to light yellow crystals. , In the body, and smelly. Implant dyes, pesticides and raw materials or intermediates for organic synthesis. Each body has a strong irritation effect and is absorbed from the skin. Acute toxicity LD50 of adjacent body: rat oral 670mg/kg Acute toxicity of opposite body LD50: rat oral 500mg, mesenchymal acute toxicity LD50: rat oral 570mg/kg, abdominal cavity 355mg/kg, subcutaneous 1390mg / kg. Parasite acute toxicity LD50: rat 500mg/kg oral, 281mg/kg intraperitoneal, 1030mg/kg subcutaneously. The Soviet Union stipulates that the initial safety level of o-chlorophenol in the atmosphere is 0.02 mg/m3. The World Health Organization (WHO) recommends that the olfactory threshold concentration of chlorophenol in absorption is 0.1μg/L.
The three isomers of chlorophenol are colorless to light yellow crystals, all of which are hardly soluble in water, soluble in ethanol and ether, and have a foul smell. Can be used as raw materials or intermediates for dyes, pesticides and organic synthesis. Each body has a strong irritation effect, and it is absorbed more from the skin.
toxicity:Acute toxicity LD50 of adjacent body: rat oral 670mg/kg, intraperitoneal 230mg/kg, subcutaneous 950mg/kg. Acute toxicity LD50 of metaphysis: rat oral 570mg/kg, intraperitoneal 355mg/kg, subcutaneous 1390mg/kg. Paratope acute toxicity LD50: 500mg/kg via oral cavity, 281mg/kg via abdominal cavity, 1030mg/kg subcutaneously.